A single vaccine is now available for immunization against diphtheria, tetanus, pertussis, polio, and Haemophilus influenzae type b. As we consider offering this to our pediatric patients, what are the vaccine's unique challenges and benefits? How does this combination vaccine compare with other options for immunization? Host Dr. Jennifer Shu examines these questions and more with Dr. Harry Keyserling, professor of pediatrics in the division of infectious diseases at Emory University School of Medicine.